A replication system domain includes all replication system components that use the same ID Server.
Your enterprise requires data management by separate groups, sites, or independent organizations.
You need to eliminate an ID Server as a single point of failure, thereby creating a fault-tolerant system.
An ID Server failure in a domain results in system degradation. New Replication Servers and databases cannot be added to a domain as long as the ID Server is shut down.
If you do use multiple replication system domains, be sure to have completely independent data environments. For example, assume you have one data environment tracking personnel, and another tracking inventory. As long as there is no data sharing or relationship between these two groups, you can create two separate domains, one for each data environment.