Use replication definitions and subscriptions to define replication across multiple alternate connections
Replication Definitions and Subscriptions for Alternate Connections
A replication definition that you create for a primary database applies to all primary connections, default and alternate, between the Replication Server that controls the replication definition and the primary database. Therefore, you must drop all replication definitions for the primary database before you drop the last primary connection to the primary database.
Moving Subscriptions Between Connections
Use alter subscription to move a subscription between replicate connections of the same replicate database that use the same Replication Server, without the need to rematerialize.