You can use the ODBC driver for the SQL Anywhere® developer edition from Sybase, provided with PowerBuilder, to access data. Other Sybase database clients also include ODBC drivers that you can access through the PowerBuilder ODBC interface. See your database documentation for details.
PowerBuilder Enterprise and PowerBuilder Professional also let you access data with any Level 1 or higher ODBC-compliant drivers obtained from a vendor other than Sybase. In most cases, these drivers will work with PowerBuilder.