When replicating with non-ASE servers, you must consider issues that are specific to the data server's role in the replication system regardless of the type or brand of a data server.
The biggest challenge in implementing a successful heterogeneous replication system is accommodating the unique characteristics of data servers that are supplied by different vendors. When a single data server acts as both a primary data server and a replicate data server (bidirectional replication), there are still more issues to consider.