PowerBuilder was tested for compatibility with a number of software products.
| Software type or product | Compatibility description |
|---|---|
| Application servers | PowerBuilder Classic has been tested with EAServer 6.3.1. |
| SQL Anywhere | PowerBuilder 12.5 has been tested with SQL Anywhere® 12.0.1. |
| PowerDesigner | PowerBuilder 12.5 has been tested with PowerDesigner® 15.3 ESD #9. |
| Microsoft .NET Framework | PowerBuilder .NET and PowerBuilder Classic are compatible with Microsoft .NET Framework 4.0 and later. |
| Web browsers | PowerBuilder Web Forms applications are fully supported in Internet Explorer 6 and later browsers. |
| Java | PowerBuilder Classic is compatible with JDK 1.5 and 1.6. |
| Ghostscript | The DataWindow Save As PDF feature has been tested with AFPL Ghostscript version 8.60. |