Use drop publication to remove a publication and all of its articles from the system tables.
Before you drop a publication, you must, at the replicate Replication Server, drop all subscriptions created against the publication.
Execute drop publication at the Replication Server that manages the source database. You must have create object permission.
drop publication pubs2_pub with primary at TOKYO_DS.pubs2
See Replication Server Reference Manual > Replication Server Commands > drop publication .