Generally, placing a table on one physical device, its nonclustered indexes on a second physical device, and the transaction log on a third physical device improves performance.
Using separate physical devices (disk controllers) reduces the time required to read or write to the disk. If you cannot devote entire devices in this way, at least restrict all nonclustered indexes to a dedicated physical device.
The log on extension to create database (or sp_logdevice) places the transaction log on a separate physical disk. Use segments to place tables and indexes on specific physical devices.