You can remove the assembly from the GAC by using the .NET Framework Configuration tool.
Removing the assembly using the .NET Framework Configuration tool
Start the .NET Framework Configuration tool. Refer to the Microsoft documentation for your specific operating system for instructions on how to start the configuration tool.
Select Assembly Cache from the tree view on the left.
Click the View List of Assemblies in the Assembly Cache link on the panel.
Find Sybase.Data.AseClient from the list of Assembly names. There may be multiple entries of this assembly corresponding to various versions deployed on this system.
Select one or more assemblies you want to remove. Right-click and select Delete. Click Yes to confirm.
Check for the Publisher policy file corresponding to the versions removed and remove these files too.
The GAC stores references made by other assemblies to a given assembly and you cannot delete the given assembly until these references are removed. You can force these references to be removed as part of the delete command. On some systems, the utility might fail to delete the assembly and complain about a pending reference to Windows Installer. This happens due to some residual values in the registry. Contact Microsoft support to get a resolution to this problem.