Determine how many domains to create and how to distribute domain components. A strategic multitenant structure for the cluster balances system-availability considerations with administrative concerns.
Domains are primarly containers for packages for a specific group of users. This group is called a tenant and can be internal to a single organization or external (for example, a hosted mobility environment).
Packages are attached to named security configurations that determine which users have access to mobile business object data, so you must create at least one security configuration and assign it to the domain for which the package is being deployed. You must identify which users require access to each package and how you will distribute the packages across the system using domains to logically partition the environment.