When you use the alter table command against a table without replication definitions, Replication Server sends warm standby databases the same information it receives from the primary server.
All options of alter table are supported. When you execute alter table at the primary, the command is replicated to the warm standby, and replication to the standby continues—no action is required in the Replication Server.
See Adaptive Server Enterprise Reference Manual: Commands > Commands > alter table for syntax and information.