There are several limitations for LOB datatypes.
You can only replicate LOB columns to Microsoft SQL Server.
You cannot define as a primary key a LOB column in the replication definition.
You cannot define as searchable a LOB column in the replication definition.
You cannot replicate stored procedures that include one of the new LOB datatypes as a parameter.
You cannot use text pointers to manipulate the data of the new LOB datatypes.
In a mixed-version environment, the primary and replicate Replication Server must have a site version of 15.2 and later and an LTL version of 710 and later.
See the Replication Server Heterogeneous Replication Guide for LOB datatype issues with non-ASE data servers. See the Replication Server Reference Manual for more information on LOB datatypes in general.