Sybase recommends that you use VMXNET 3 virtual network interface cards (NICs) for your Adaptive Server running on Windows virtual machines.
During internal testing, Sybase noted performance improvement for sites using the VMXNET3 NICs running on the Windows guest operating system compared to sites using the default E1000 adapter.
VMXNET3 supports an adaptive interrupt coalescing algorithm, which helps drive high throughputs to virtual machines using multiple vCPUs with parallelized workloads (for example, multiple threads).